학력

• 원광대학교 의과대학
• 의학석사

경력 및 연수

• 삼성서울병원 외과 전공의
• 삼성서울병원 소화기외과 전임의
• 제주대학교 의학전문대학원 교수
• 제주대학교 의학전문대학원 임상의학주임교수
• 호주(Royal Melbourne Hospital) 연수 - 2006.2.1~ 2007.6.30
• 제주대학교병원 교육연구부장 역임
• 제주지역암센터장 역임
• 제주대학병원 외과 과장

학회활동

• 대한외과학회 정회원
• 대한대장항문학회 정회원
• 대한대장항문학회 교육수련위원회 위원

Exression Profile of LGR5 and its prognostic significance in colrectal cancer progrssion /AMERICAN JOURNAL OF PATHOLOGY/ 201810

Prognostic Significance of EPHB2 Expression in Colorectal Cancer Progression /JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE/ 201807

Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells /Oncotarget/ 201804

What is the meaning of anaphase-promoting complex 7 in malignant neoplasms? /ANNALS OF COLOPROCTOLOGY/ 201708

Aurora kinase A is a prognostic marker in colorectal adenocarcinoma /JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE/ 201701

Prognostic significance of stromal GREM1 expression in colorectal cancer /HUMAN PATHOLOGY/ 201612

"The effect of (1S,2S,3E,7E,11E)-3,7,11,15-Cembratraen-17,2-Olide" /BIOMOLECULES & THERAPEUTICS/ 201611

How can we ameliorate the role of colorectal cancer awareness month? /Annals of Coloproctology/ 201610

Interaction of DNA demethylase and histone /Oncotarget/ 201606

The Study for Incidence trends of Colorectal cancer in Jeju-do /한국산학기술학회논문지/ 201605

solitary rectal ulcer syndrome mimicking rectal cancer /EWHA MEDICAL JOURNAL/ 201601

The 2013-2015 Ebola outbreak in west africa /Journal of Bacteriology and Virology/ 201511

Single Cavernous Hemangioma of the Small Bowel Diagnosed by Using Capsule Endoscopy in a Child with Chronic Iron-Deficiency Anemia /Clinical Endoscopy/ 201507

Involvement of glutathione and glutathione metabolizing enzymes in human colorectal cancer cell lines and tissues /MOLECULAR MEDICINE REPORTS/ 201506

Camptothecin suppresses expression of matrix metalloproteinase-9 and vascular endothelial growth factor in DU145 cells through PI3K/Akt-mediated inhibition of NF-kappa B activity and Nrf2-dependent induction of HO-1 expression /ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY/ 201505

제주특별자치도 암 환자의 역학적인 특성에 관한 연구 /한국산학기술학회논문지/ 201502

Epigenetic alterations are involved in the overexpression of glutathione S-transferase pi-1 in human colorectal cancers /INTERNATIONAL JOURNAL OF ONCOLOGY/ 201409

Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation /CELL DEATH & DISEASE/ 201408

18 beta-Glycyrrhetinic acid suppresses TNF-alpha induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-kappa B pathway /TOXICOLOGY IN VITRO/ 201408

preliminary results on using array comparative hybridization of colorectal cancer /THE JOURNAL OF MEDICINE AND LIFE SCIENCE/ 201402

Downregulation of NO and PGE2 in LPS-stimulated BV2 microglial cells by trans-isoferulic acid via suppression of PI3K/Akt-dependent NF-κB and activation of Nrf2-mediated HO-1. /INTERNATIONAL IMMUNOPHARMACOLOGY/ 201401

Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells. /GENE/ 201307

재가암환자 질병관련 특성에 따른 증상 경험 및 제공받은 서비스 분석 /ASIAN ONCOLOGY NURSING/ 201306

20-O-(β-D-glucopyranosyl)-20(S)-protopanaxadiol induces apoptosis via induction of endoplasmic reticulum stress in human colon cancer cells /ONCOLOGY REPORTS/ 201304

Study of Metabolic Profiling Changes in Colorectal Cancer Tissues Using 1D H-1 HR-MAS NMR Spectroscopy /BULLETIN OF THE KOREAN CHEMICAL SOCIETY/ 201302

The green algae Ulva fasciata Delile extract induces apoptotic cell death in human colon cancer cells /IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL/ 201301

Mode of primary cancer detection as an indicator of screening practice for second primary cancer in cancer survivors: a nationwide survey in Korea /BMC CANCER/ 201211

Involvement of heme oxygenase-1 in Korean colon cancer. /TUMOR BIOLOGY/ 201208

"(1S,2S,3E,7E,11E)-3,7,11,15-Cembratetraen-17,2-olide, a Cembrenolide Diterpene from Soft Coral Lobophytum sp., Inhibits Growth and Induces Apoptosis in Human Colon Cancer Cells through Reactive Oxygen Species Generation" /BIOLOGICAL & PHARMACEUTICAL BULLETIN/ 201206

Examination of Colorectal Cancer Patient's Ascites by 2D-Electrophoresis /THE JOURNAL OF MEDICINE AND LIFE SCIENCE/ 201206

Apigenin decreases cell viability and telomerase activity in human leukemia cell lines /FOOD AND CHEMICAL TOXICOLOGY/ 201205

Inhibitory effects of Carpinus tschonoskii leaves extract on CpG-stimulated pro-inflammatory cytokine production in murine bone marrow-derived macrophages and dendritic cells /IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL/ 201204

Capsaicin sensitizes TRAIL-induced apoptosis through Sp1-mediated DRS up-regulation: Involvement of Ca2+ influx /TOXICOLOGY AND APPLIED PHARMACOLOGY/ 201202

캡슐내시경으로 진단한 Peutz-Jeghers 증후군 /INTESTINAL RESEARCH/ 201012

"compound K, a metabolite of Ginseng saponin, induces mitocondria" /INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES/ 201012

"Three novel germline mutations in MLH1 and MSH2 in families with Lynch syndrome living on Jeju island, Korea" /BMB REPORTS/ 201010

제주지역 암환장의 의료서비스 요구도 및 만족도 분석 /한국호스피스완화의료학회지/ 201009

Ginseng saponin metabolite induces apoptosis in MCF-7 breast cancer cells through the modulation of AMP-activated protein kinase /ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY/ 201009

Butin reduces oxidative stress-induced mitochondrial dysfunction via scavenging of reactive oxygen species /FOOD AND CHEMICAL TOXICOLOGY/ 201003

Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation /CANCER LETTERS/ 201002

Induction of matrix metalloproteinase-9 by galectin-7 through p38 MAPK signaling in HeLa human cervical epithelial adenocarcinoma cells /ONCOLOGY REPORTS/ 200910

A study on electrical impedance technique for breast cancer detection /Cancer Prevention Research/ 200910

Induction of matrix metalloproteinase-9 by galectin-7 through p38 MAPK signaling in HeLa human cervical epithelial adenocarcinoma cells /ONCOLOGY REPORTS/ 200909

"Effect of Compound K, a Metabolite of Ginseng Saponin, Combined with gamma-Ray Radiation in Human Lung Cancer Cells in Vitro and in Vivo" /JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY/ 200907

Protective mechanism of KIOM-4 against streptozotocin induced diabetic cells: Involvement of heme oxygenase-1 /BIOTECHNOLOGY AND BIOPROCESS ENGINEERING/ 200906

"Antioxidant properties of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose from Elaeocarpus sylvestris var. ellipticus" /FOOD CHEMISTRY/ 200906

Induction of Apoptosis in SNU-16 Human Gastric Cancer Cells by the Chloroform Fraction of an Extract of Dangyuja (Citrus grandis) Leaves /J Korean Soc. appl/ 200906

"Preventive effect of 7,8-dihydroxyflavone against Oxidative Stress Induced Genotoxicity" /BIOLOGICAL & PHARMACEUTICAL BULLETIN/ 200902

Cellular protection of morin against the oxidative stress induced by hydrogen peroxide /CHEMICO-BIOLOGICAL INTERACTIONS/ 200902

췌장 고형 가유두상 종양의 임상병리학적 고찰 /대한외과학회지/ 200606

복부둔상 후 발생한 상장간막동맥 가성동맥류의 지연출혈 /대한외과학회지/ 200406

췌장의 침윤성 관선암종과 관내 유두상 점액 종양에서 S100A4의 발현 /대한외과학회지/ 200406

대장직장암 근치수술 후 흉부단순촬영은 폐전이 진단에 유용한가? /대한대장항문학회지/ 200406

대장 및 직장암의 간전이 시 간절제와 고주파 온열치료의 임상적 비교 /대한대장항문학회지/ 200406

간세포함 수술 후 하부 담관에 발생한 종양색전의 수술적 치료 /한국간담췌외과학회지/ 200403

2000년 제주도 위암 발생자의 형태조직학적 특성 /제주의대학술지/ 200402

대장의 악성종양의 치료에서 복강경 술식이 적합한 방법이 될수 있는가 /제주의대학술지/ 200402

수술사망없이 연속된 254예의 췌십이지장 절제술 /대한외과학회지/ 200212

췌십이지장 절제술 후 발생한 가성동맥류 8예 /대한외과학회지/ 200212

위 신경초종 1예 /대한위암학회지/ 200212

췌관내 유두상 점액성 종양의 외과적치료 /대한외과학회지/ 200208

충수돌기 점액낭종에서 시행된 복강경 회맹절제술 1예 /대한내시경복강경학회지/ 200206

T1 T2 직장암에 대한 경항문 내시경 미세수술과 광범위 절제술의 치료성적비교 /대한대장항문학회지/ 200206

대장의 종양에 대한 복강경 전방절제술의 임상적경험 : 개복술과의 비교분석 /대한내시경복강경외과학회지/ 200205

대장암 및 직장암의 간 전이 시 고주파 온열 치료의 단기결과 /대한대장항문학회지/ 200205

경항문 미세수술의 임상적 고찰 /대한대장항문학회지/ 200205

소아외과 /소아림프관종의OK-432병변내주사요법/ 200110

간이식수술에서 T-TUBE 를 사용하지않은 담도재건술식 /대한이식학회지/ 199802